| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588369 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
Two pyranoxanthones (16 and 20) showed the greatest activity against the KBvin multidrug resistant (MDR) cell line with IC50 values of 0.9 and 0.8 μg/mL, respectively. An angular 3-methyl-3-prenyl pyranoxanthone (17) selectively inhibited elastase release with 200 times more potency than PMSF, the positive control.
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Authors
Chiao-Ting Yen, Kyoko Nakagawa-Goto, Tsong-Long Hwang, Susan L. Morris-Natschke, Kenneth F. Bastow, Yang-Chang Wu, Kuo-Hsiung Lee,