Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10588383 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
A series of hydroxybenzoxazole derivatives was synthesized, and their c-Met kinase inhibitory activity was evaluated. Described herein is a potent c-Met inhibitor by structural modification of the parent benzoxazole scaffold, with particular focus on the hydroxyl substituent of the benzoxazole moiety.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jongkook Lee, Sun-Young Han, Heejung Jung, Jeon Yang, Jie-Won Choi, Chong Hack Chae, Chi Hoon Park, Sang Un Choi, Kwangho Lee, Jae Du Ha, Chong Ock Lee, Jae Wook Ryu, Hyoung Rae Kim, Jong Sung Koh, Sung Yun Cho,