Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10588442 | Bioorganic & Medicinal Chemistry Letters | 2012 | 6 Pages |
Abstract
Small peptidic kappa agonists were covalently linked to the reactive lysine of the CovX antibody to create compounds having potent activity at the kappa receptor with greatly extended half-life when compared to the parent peptide as exemplified by compound 20.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Lee R. Roberts, Kevin Brady, Amy Brown, Doreen Davey, Lijin Feng, Hanhua Huang, Dingguo Liu, Laia Malet, Gordon McMurray, Anne Phelan, Ken Saunders, Abhijit Bhat,