Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10588586 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
A new class of potent and selective 5-HT2C agonists for the treatment of metabolic disorders is described. Optimization of selectivity, permeability and hERG interaction is discussed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Heather Tye, Stephan G. Mueller, Juergen Prestle, Stefan Scheuerer, Marcus Schindler, Bernd Nosse, Natacha Prevost, Christopher J. Brown, Alexander Heifetz, Clemens Moeller, Anna Pedret-Dunn, Mark Whittaker,