| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588595 | Bioorganic & Medicinal Chemistry Letters | 2011 | 10 Pages |
Abstract
CoMSIA model of 2,6-substituted-4-monosubstituted aminopyrimidine antagonists of prostaglandin D2 receptor (DP1) is reported. The utility of this QSAR model in chemical lead optimization is discussed.
Related Topics
Physical Sciences and Engineering
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Authors
Lan Mu, Joacy Aguiar, Ali Ardati, Bin Cao, Charles J. Gardner, Tim Gillespy, Keith Harris, Sungtaek Lim, Robert Marcus, Isabelle Morize, Ashfaq Parkar, David Stefany, Yi Li, Roy J. Vaz, Dragan A. Cirovic,