| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588642 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
A series of 2,4-diphenyl-1H-imidazole analogs have been synthesized and displayed potent human CB2 agonist activity. Many of these analogs showed high functional selectivity over human CB1 receptors. The syntheses, structure-activity relationships, and selected pharmacokinetic data of these analogs are described.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shu-Wei Yang, Jennifer Smotryski, Julius Matasi, Ginny Ho, Deen Tulshian, William J. Greenlee, Rossella Brusa, Massimiliano Beltramo, Kathleen Cox,