Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10588659 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
TGF-β signaling pathway inhibitor and potential anti-nephropathic agent SMP-534 was successfully converted to a new class of benzoylpyrrole-based PPARα/γ activators as an anti-diabetic agent. Compound 10sNa showed a favorable blood glucose-lowering effect without body weight gain.
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Organic Chemistry
Authors
Kantaro Ushiroda, Katsunori Maruta, Makoto Kitoh, Kiyotaka Iwai, Jun Nagamine, Atsushi Tsuchida, Mutsuo Taiji, Ryu Nagata,