Article ID Journal Published Year Pages File Type
10588663 Bioorganic & Medicinal Chemistry Letters 2011 6 Pages PDF
Abstract
Various phenolic C-glycosides were evaluated for their in vitro and in vivo antihyperglycemic activity employing glucose uptake by rat muscle cell lines (L-6) and low dosed-streptozotocin-induced diabetic rats, respectively. The compound 24 lowered the blood glucose levels by 34.9% and 33.6% during 5 h and 24 h, respectively, at the dose of 25 mg/kg body weight which is comparable to standard antidiabetic drug metformin.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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