| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588677 | Bioorganic & Medicinal Chemistry Letters | 2011 | 5 Pages |
Abstract
A SAR was developed for a novel series of heterocyclic containing compounds. Potent CXCR4 antagonists were identified based on anti-HIV-1 activity and Ca2+ flux inhibition that also displayed good pharmacokinetics.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Renato Skerlj, Gary Bridger, Ernie McEachern, Curtis Harwig, Chris Smith, Trevor Wilson, Duane Veale, Helen Yee, Jason Crawford, Krystyna Skupinska, Rossana Wauthy, Wen Yang, Yongbao Zhu, David Bogucki, Maria Di Fluri, Jonathon Langille, Dana Huskens,