| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588679 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Two new 3-alkylpyridine alkaloids, pyrinodemins E (1) and F (2), were isolated from an Okinawan marine sponge Amphimedon sp. and the structures of 1 and 2 were elucidated on the basis of spectroscopic data. Pyrinodemins E (1) and F (2) were novel 3-alkylpyridine alkaloids possessing a 4-(methoxyamino)piperidinone moiety and an indol-3-glyoxylamide moiety, respectively. Pyrinodemin E (1) showed cytotoxicity against P388 and L1210 murine leukemia cells.
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Organic Chemistry
Authors
Ken'ichi Kura, Takaaki Kubota, Jane Fromont, Jun'ichi Kobayashi,