Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10588697 | Bioorganic & Medicinal Chemistry Letters | 2011 | 4 Pages |
Abstract
Structure-activity relationship (SAR) of the α-amino acid residue and identification of (S)-2,3-diaminopropanoic acid (DAP) replacements of potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonists are described.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Min Zhong, Emily J. Hanan, Wang Shen, Minna Bui, Michelle R. Arkin, Kenneth J. Barr, Marc J. Evanchik, Ute Hoch, Jennifer Hyde, Jose R. Martell, Johan D. Oslob, Kumar Paulvannan, Saileta Prabhu, Jeffrey A. Silverman, Jasmin Wright, Chul H. Yu, Jiang Zhu,