| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588775 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
A structure-activity relationship study of a screening hit has led to the identification of bisarylureas as potent inhibitors of Streptococcus agalactiae Stk1. As this target has been directly linked to bacterial virulence, these inhibitors can be considered as a promising step towards antivirulence drugs.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Mayalen Oxoby, François Moreau, Lionel Durant, Alexis Denis, Jean-Marie Genevard, Vanida Vongsouthi, Sonia Escaich, Vincent Gerusz,