| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588781 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
Significant improvement in metabolic stability on the pyrazolopiperidine scaffold over the original series were achieved and this stability improvement translated in an improved in vivo efficacy.
Related Topics
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Authors
Xiaocong M. Ye, Andrei W. Konradi, Jenifer Smith, Danielle L. Aubele, Albert W. Garofalo, Jennifer Marugg, Marty L. Neitzel, Chris M. Semko, Hing L. Sham, Minghua Sun, Anh P. Truong, Jing Wu, Hongbin Zhang, Erich Goldbach, John-Michael Sauer,