| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588789 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
A series of novel bicyclo[3.3.0]octane derivatives have been synthesized and found to be dipeptidyl peptidase 4 (DPP-4) inhibitors. Compounds 10a and 10b demonstrate good efficacies in oral glucose tolerance tests.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Synthesis and biological evaluation of bicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetes](/preview/png/10588789.png "First Page Preview: Synthesis and biological evaluation of bicyclo[3.3.0] octane derivatives as dipeptidyl peptidase 4 inhibitors for the treatment of type 2 diabetes")
Authors
Tang Peng Cho, Lin Zhi Gang, Yang Fang Long, Wang Yang, Wang Qian, Zhang Lei, Luo Jing Jing, Feng Ying, Yan Pang Ke, Leng Ying, Feng Jun,