| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588798 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
Optimization and further SAR exploration of the biaryl amide series resulted in the discovery of orally bioavailable, CNS-penetrant M1 agonists with excellent potency and subtype selectivity.
Related Topics
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Authors
Brian Budzik, Vincenzo Garzya, Dongchuan Shi, Graham Walker, Yann Lauchart, Adam J. Lucas, Ralph A. Rivero, Christopher J. Langmead, Jeannette Watson, Zining Wu, Ian T. Forbes, Jian Jin,