Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10588833 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
In the present investigation novel series of 4-substituted-1-(8-hydroxy-quinolin-5-yl)-azetidin-2-ones are synthesized, screened for in vitro anti-filarial activity against Brugia malayi. In silico molecular docking analysis of title compounds performed in to the active site of enzyme glutathione-S-transferases.
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Authors
Santosh S. Chhajed, Puranik Manisha, Virupaksha A. Bastikar, Haldar Animeshchandra, V.N. Ingle, Chandrashekhar D. Upasani, Sachin S. Wazalwar,