Article ID Journal Published Year Pages File Type
10588841 Bioorganic & Medicinal Chemistry Letters 2010 6 Pages PDF
Abstract
A novel series of [6-chloro-2-trifluoromethyl-7-aryl-7H-imidazo[1,2-a]imidazol-3-ylmethyl]-dialkylamines was discovered as potent CRF1R antagonists. The optimization of binding affinity in the series by the parallel reaction approach is discussed herein.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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