Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10588853 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
Synthesis of novel β-lactam fused spiroisoxazolidine chromanones and tetralones ring systems has been achieved by intermolecular 1,3-dipolar cycloaddition reaction of bicyclic nitrone with unusual dipolarophiles, arylidene chromanones/tetralones under different reaction conditions. The synthesized compounds were evaluated for antimicrobial activities. It was observed that two of the synthesized compounds exhibited relatively good antibacterial and antifungal activities.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Natarajan Arumugam, Raghavachary Raghunathan, Vellaisamy Shanmugaiah, Narayanasamy Mathivanan,