Article ID Journal Published Year Pages File Type
10588853 Bioorganic & Medicinal Chemistry Letters 2010 5 Pages PDF
Abstract
Synthesis of novel β-lactam fused spiroisoxazolidine chromanones and tetralones ring systems has been achieved by intermolecular 1,3-dipolar cycloaddition reaction of bicyclic nitrone with unusual dipolarophiles, arylidene chromanones/tetralones under different reaction conditions. The synthesized compounds were evaluated for antimicrobial activities. It was observed that two of the synthesized compounds exhibited relatively good antibacterial and antifungal activities.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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