| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10588866 | Bioorganic & Medicinal Chemistry Letters | 2010 | 4 Pages |
Abstract
In search of a serotonin 5-HT7 radiotracer for positron emission tomography, we developed 1-{2-[(2S)-1-(phenylsulfonyl)pyrrolidin-2-yl]ethyl}piperidin-4-yl 4-fluorobenzoate. After labeling in good yield with fluorine-18 via nitro for fluorine exchange, preliminary biological experiments with autoradiographies failed to evidence any specific 5-HT7 receptor delineation.
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Authors
Julien Andriès, Laëtitia Lemoine, Alice Mouchel-Blaisot, Sandrine Tang, Mathieu Verdurand, Didier Le Bars, Luc Zimmer, Thierry Billard,