Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10588907 | Bioorganic & Medicinal Chemistry Letters | 2010 | 5 Pages |
Abstract
New asterosaponins archasterosides A (1), B (2), and the known regularoside A (3) were isolated from the Vietnamese starfish Archaster typicus and structurally elucidated by extensive NMR techniques and chemical transformations. Compounds 1-3 showed moderate cytotoxic activities against HeLa and mouse JB6 P+ Cl41 cell lines. The most active, 2, induced basal AP-1- and p53-, but not NF-κB-transcriptional activations in JB6 Cl41 cells.
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Authors
Alla A. Kicha, Natalia V. Ivanchina, Trinh T.T. Huong, Anatoly I. Kalinovsky, Pavel S. Dmitrenok, Sergey N. Fedorov, Sergey A. Dyshlovoy, Pham Q. Long, Valentin A. Stonik,