Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10590310 | Bioorganic & Medicinal Chemistry Letters | 2015 | 4 Pages |
Abstract
We have developed a simple and efficient system-based on quencher-free molecular aptamer beacons (QF-MABs)-for probing ATP. In the absence of ATP, the fluorescence of a pyrene fluorophore on the loop position of the optimal QF-MAB was quenched by the neighboring nucleobases; in its presence, fluorescence was recovered, due to a conformational change in the secondary structure of the QF-MAB.
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Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jung Woo Park, Yoojin Park, Byeang Hyean Kim,