Article ID Journal Published Year Pages File Type
10590837 Bioorganic & Medicinal Chemistry Letters 2015 7 Pages PDF
Abstract
A series of hybrids from 4-anilinoquinazoline and hydroxamic acid were discovered as potent dual inhibitors of VEGFR-2 and HDAC. Compound 6l exhibited the most potent inhibitory activities with IC50 value of 84 nM and 2.8 nM against VEGFR-2 and HDAC, respectively.
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Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
Hybrids from 4-anilinoquinazoline and hydroxamic acid as dual inhibitors of vascular endothelial growth factor receptor-2 and histone deacetylase
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