Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5

Article ID	Journal	Published Year	Pages	File Type
10590868	Bioorganic & Medicinal Chemistry Letters	2015	22 Pages	PDF

Keywords

PEPCK CPT-cAMP 2-(N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino)-2-deoxyglucose G6Pase T2DM Hdac5 2-NBDG AMPK cyclic AMP-responsive element-binding protein FOXO1 MEF2 CREB CRTC2 FBS AMP-activated protein kinase chromatin immunoprecipitation Glucose uptake Forkhead box O1 Type II diabetes mellitus fetal bovine serum myocyte enhancer factor-2 phosphoenolpyruvate carboxykinase CHiP Glut-4 glucose-6-phosphatase glucose transporter-4 Gluconeogenesis

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5

Authors

Woo-Duck Seo, Ji Hae Lee, Yaoyao Jia, Chunyan Wu, Sung-Joon Lee,