Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications

Article ID	Journal	Published Year	Pages	File Type
10590913	Bioorganic & Medicinal Chemistry Letters	2015	5 Pages	PDF

Keywords

SAR IRAK4 Serine–threonine kinase Kinase inhibitor

Related Topics

Physical Sciences and Engineering Chemistry Organic Chemistry

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Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications

Authors

Jongwon Lim, Michael D. Altman, James Baker, Jason D. Brubaker, Hongmin Chen, Yiping Chen, Melanie A. Kleinschek, Chaomin Li, Duan Liu, John K.F. Maclean, Erin F. Mulrooney, Jeremy Presland, Larissa Rakhilina, Graham F. Smith, Ruojing Yang,