| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10590940 | Bioorganic & Medicinal Chemistry Letters | 2014 | 5 Pages |
Abstract
Scaffold hopping of antifungal natural product sampangine yielded thiophene derivative S2 with broad-spectrum antifungal activity and improved water solubility. Particularly, compound S2 showed good activity against Aspergillus fumigatus and Cryptococcus neoformans.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Zhigan Jiang, Na Liu, Guoqiang Dong, Yan Jiang, Yang Liu, Xiaomeng He, Yahui Huang, Shipeng He, Wei Chen, Zhengang Li, Jianzhong Yao, Zhenyuan Miao, Wannian Zhang, Chunquan Sheng,