| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10591168 | Bioorganic & Medicinal Chemistry Letters | 2014 | 13 Pages |
Abstract
Halogenated diarylacetylenes 2 (X1-5 = H, F and/or Cl and Y = 4-NHCH3 or 4-N(CH3)2) inhibit that inhibit the expression of Wnt target genes, such as c-myc, at 1-3 μM concentrations and induce the cyclin-dependent kinase inhibitor-1 (i.e., p21(Wif1/Cip1)).
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Authors
Vitaliy M. Sviripa, Wen Zhang, Liliia M. Kril, Alice X. Liu, Yaxia Yuan, Chang-Guo Zhan, Chunming Liu, David S. Watt,