| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10591285 | Bioorganic & Medicinal Chemistry Letters | 2013 | 6 Pages |
Abstract
The rhizomes of Alpinia pahangensis Ridley yielded a new bis-labdanic diterpene for which the name pahangensin A (1) was proposed along with a new labdane diterpene, pahangensin B (2). Their structures were elucidated by spectroscopic methods including, 1D and 2D NMR techniques and LCMS-IT-TOF analysis. Pahangensin A (1) was found to be an antibacterial agent against Staphylococcus aureus, Bacillus cereus and Bacillus subtilis with MIC values less than 100 μg/mL, respectively. Pahangensin B (2) exhibited antibacterial activity (MIC <100 μg/mL) against B. cereus.
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Authors
Yasodha Sivasothy, Halijah Ibrahim, Audra Shaleena Paliany, Siti Aisyah Alias, Khalijah Awang,