| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10591492 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
A series of small molecules with a piperidinyl core were synthesized and tested for binding affinity (IC50) at human Neuropeptide Y Y2 receptor. Various amide related analogs (ureas, reversed amides, and sulfonamides) were evaluated. Several potent and selective NPY Y2 antagonists were identified.
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Authors
Wenying Chai, Victoria D. Wong, Diane Nepomuceno, Pascal Bonaventure, Timothy W. Lovenberg, Nicholas I. Carruthers,