Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10591700 | Bioorganic & Medicinal Chemistry Letters | 2013 | 5 Pages |
Abstract
A series of CCR1 antagonists based upon spirocyclic compounds 1b and 2b were synthesised in which substituted aniline moiety was replaced with substituted benzamides. In vitro data revealed that CCR1 potency could be retained in such compounds.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Nafizal Hossain, Svetlana Ivanova, Jonas Bergare, Marguérite Mensonides-Harsema, Martin E. Cooper,