| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10591915 | Bioorganic & Medicinal Chemistry Letters | 2013 | 6 Pages |
Abstract
A series of benzoxazole compounds containing oxamic acid were synthesized and screened for the PTP1B inhibition. Compound 31d showed best biochemical potency (Ki) of 6.7 μM. Structure-activity relationship were explained with the help of molecular modeling approach.
Related Topics
Physical Sciences and Engineering
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Authors
Arun P. Chandrasekharappa, Sangamesh E. Badiger, Pramod K. Dubey, Sunil K. Panigrahi, Sekhar Reddy V.V.V. Manukonda,