Article ID Journal Published Year Pages File Type
10592141 Bioorganic & Medicinal Chemistry Letters 2014 4 Pages PDF
Abstract
A benzoylthiourea-pyrrolidine catalyst was developed for the asymmetric Michael addition of ketones to chalcones. The corresponding products were obtained in high yields with high level of diastereoselectivities (up to 99:1 dr) and high level of enantioselectivities (up to 94% ee) under mild conditions.
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Physical Sciences and Engineering Chemistry Organic Chemistry
Preview
A chiral benzoylthiourea-pyrrolidine catalyst for the highly enantioselective Michael addition of ketones to chalcones
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