Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10592141 | Bioorganic & Medicinal Chemistry Letters | 2014 | 4 Pages |
Abstract
A benzoylthiourea-pyrrolidine catalyst was developed for the asymmetric Michael addition of ketones to chalcones. The corresponding products were obtained in high yields with high level of diastereoselectivities (up to 99:1 dr) and high level of enantioselectivities (up to 94% ee) under mild conditions.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Shu-rong Ban, Xi-xia Zhu, Zhi-ping Zhang, Qing-shan Li,