Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10592348 | Bioorganic & Medicinal Chemistry Letters | 2014 | 6 Pages |
Abstract
A series of 11 novel amides of salinomycin were synthesized for the first time. All the obtained compounds were found to show potent antiproliferative activity against human cancer cell lines including the drug-resistant cancer cells. Four new salinomycin derivatives revealed good antibacterial activity against clinical isolates of methicillin-resistant Staphylococcus epidermidis (MRSE).
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Authors
MichaÅ Antoszczak, Ewa Maj, Joanna StefaÅska, Joanna Wietrzyk, Jan Janczak, Bogumil Brzezinski, Adam HuczyÅski,