Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10592379 | Bioorganic & Medicinal Chemistry Letters | 2014 | 5 Pages |
Abstract
Bisindole derivatives 1-17 have been synthesized and evaluated for their in vitro β-glucuronidase inhibitory potential. Some of these derivatives showed β-glucuronidase inhibitory activity more potent than the standard d-sachharic acid. In addition, molecular docking studies were also carried out using the GOLD 3.0 program to predict their structure-activity relationship.
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Authors
Khalid Mohammed Khan, Fazal Rahim, Abdul Wadood, Muhammad Taha, Momin Khan, Shagufta Naureen, Nida Ambreen, Shafqat Hussain, Shahnaz Perveen, Mohammad Iqbal Choudhary,