Article ID Journal Published Year Pages File Type
10592379 Bioorganic & Medicinal Chemistry Letters 2014 5 Pages PDF
Abstract
Bisindole derivatives 1-17 have been synthesized and evaluated for their in vitro β-glucuronidase inhibitory potential. Some of these derivatives showed β-glucuronidase inhibitory activity more potent than the standard d-sachharic acid. In addition, molecular docking studies were also carried out using the GOLD 3.0 program to predict their structure-activity relationship.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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