| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10592382 | Bioorganic & Medicinal Chemistry Letters | 2014 | 4 Pages |
Abstract
OSW-1 is a steroidal saponin, which has emerged as an attractive anticancer agent with highly cancer cell selective activity. A fluorescent analog was prepared from the natural product to analyze its cellular uptake and localization. We found that the fluorescent analog is rapidly internalized into cells and is primarily distributed in endoplasmic reticulum and Golgi apparatus.
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Authors
Rika Yamada, Tomoya Takeshita, Masato Hiraizumi, Daisuke Shinohe, Yoshihiro Ohta, Kaori Sakurai,