Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10592398 | Bioorganic & Medicinal Chemistry Letters | 2015 | 5 Pages |
Abstract
Molecules related to the dual orexin receptor antagonist filorexant were transformed into compounds that were selective for the OX2R subtype leading to MK-8133.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Scott D. Kuduk, Jason W. Skudlarek, Christina N. DiMarco, Joseph G. Bruno, Mark H. Pausch, Julie A. O'Brien, Tamara D. Cabalu, Joanne Stevens, Joseph Brunner, Pamela L. Tannenbaum, Susan L. Garson, Alan T. Savitz, Charles M. Harrell, Anthony L. Gotter,