| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10592484 | Bioorganic & Medicinal Chemistry Letters | 2012 | 6 Pages |
Abstract
The receptor model-supported design, synthesis and multi-parameter optimization of novel quinazoline derivatives as MCHR1 antagonists are described. The in vivo proof of principle for weight loss is exemplified with compound 42 from this series.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Sanjita Sasmal, Gade Balaji, Hariprasada R. Kanna Reddy, D. Balasubrahmanyam, Gujjary Srinivas, ShivaKumar Kyasa, Pradip K. Sasmal, Ish Khanna, Rashmi Talwar, J. Suresh, Vikram P. Jadhav, Syed Muzeeb, Dhanya Shashikumar, K. Harinder Reddy,