| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10592577 | Bioorganic & Medicinal Chemistry Letters | 2014 | 5 Pages |
Abstract
A novel series of substituted 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles were investigated as N-type calcium channel blockers (Cav2.2 channels), a chronic pain target. One compound was active in vivo in the rat CFA pain model.
Keywords
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
![Discovery and SAR of a novel series of 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles as N-type calcium channel inhibitors](/preview/png/10592577.png "First Page Preview: Discovery and SAR of a novel series of 2,4,5,6-tetrahydrocyclopenta[c]pyrazoles as N-type calcium channel inhibitors")
Authors
Michael P. Winters, Nalin Subasinghe, Mark Wall, Edward Beck, Michael R. Brandt, Michael F.A. Finley, Yi Liu, Mary Lou Lubin, Michael P. Neeper, Ning Qin, Christopher M. Flores, Zhihua Sui,