| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10592608 | Bioorganic & Medicinal Chemistry Letters | 2014 | 4 Pages |
Abstract
The discovery of a novel series of cyclopenta[b]furans as CCR2 inhibitors is discussed. This series has excellent CCR2 potency and PK characteristics, and good cardiovascular safety.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
![The discovery and SAR of cyclopenta[b]furans as inhibitors of CCR2](/preview/png/10592608.png "First Page Preview: The discovery and SAR of cyclopenta[b]furans as inhibitors of CCR2")
Authors
Michael P. Winters, Christopher A. Teleha, Fu-An Kang, David McComsey, John C. O'Neill, Cuifen Hou, Thomas Kirchner, Ping Wang, Dana Johnson, Zhihua Sui,