Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10592631 | Bioorganic & Medicinal Chemistry Letters | 2014 | 5 Pages |
Abstract
N-Substituted amino-2(5H)-oxazolones A are a novel class of insecticides acting as nicotinic acetylcholine receptor (nAChR) agonists and show potent activity against hemipteran insect species. Here we report the discovery and preparation of this class of chemistry. Our efforts in SAR elucidation, biological activity evaluation, as well as mode-of-action studies are also presented.
Related Topics
Physical Sciences and Engineering
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Authors
Wenming Zhang, James D. Barry, Daniel Cordova, Stephen F. McCann, Eric A. Benner, Kenneth A. Hughes,