Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10592682 | Bioorganic & Medicinal Chemistry Letters | 2016 | 4 Pages |
Abstract
Reported herein are a series of reverse indoles that represent novel non-steroidal mineralocorticoid receptor (MR) antagonists. The key structure-activity relationships (SAR) and acute pharmacodynamic efficacy in an acute natriuresis rodent model are presented.87
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Authors
Anthony K. Ogawa, Ellen Vande Bunte, Rudrajit Mal, Ping Lan, Zhongxiang Sun, Alejandro Crespo, Judyann Wiltsie, Joseph Clemas, Jack Gibson, Lisa Contino, JeanMarie Lisnock, Gaochao Zhou, Margarita Garcia-Calvo, Nina Jochnowitz, Xiuying Ma, Yi Pan,