Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10592742 | Bioorganic & Medicinal Chemistry Letters | 2014 | 6 Pages |
Abstract
Six molecules were obtained by the combination of three biologically and medicinally significant moieties-indole, chrysin and pyrazole. Bio-evaluation of these hybrid molecules showed significant inhibition of COX-2 enzymatic activity over that of COX-1 and appreciable anti-nociceptive activity, checked at swiss albino mice.
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Authors
Palwinder Singh, Shaveta Shaveta, Surbhi Sharma, Rajbir Bhatti,