| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10592769 | Bioorganic & Medicinal Chemistry Letters | 2014 | 5 Pages |
Abstract
The synthesis and characterization of some new titanocene-complexes, having a ethenyl-phenoxide or a benzyl group as substituents of the cyclopentadienyl rings, are reported. The synthesized compounds have been evaluated for their cytotoxic potential against two human breast cancer cell lines, that is: MCF7 and SkBr3. Most of these compounds have shown significant cytotoxic effects, compared to cisplatin, in MTT-based cell tests.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Carmela Saturnino, Esther Sirignano, Antonio Botta, Maria Stefania Sinicropi, Anna Caruso, Assunta Pisano, Rosamaria Lappano, Marcello Maggiolini, Pasquale Longo,