| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10592995 | Bioorganic & Medicinal Chemistry Letters | 2013 | 4 Pages |
Abstract
A series of thiosemicarbazone-triazole hybrids 1a-h are efficiently synthesised and evaluated for their influence on the expression of genes, cpt-1, acc-1 and pgc-1, which are essential in lipid metabolism. The test results show that hybrids 1c and 1g exhibited relatively high influence on the expression of cpt-1 and pgc-1 and suppression of acc-1 as desired.
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Authors
Henok H. Kinfe, Yonas H. Belay, Jitcy S. Joseph, Emmanuel Mukwevho,