Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10593185 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
A series of novel cyclic amine-substituted benzoic acid derivatives were synthesized and evaluated for their PPARα agonist activity. SAR studies led to the identification of a potent PPARα agonist (S)-4f with high selectivity.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Masahiro Nomura, Kazuhiro Yumoto, Takehiro Shinozaki, Shigeki Isogai, Yasuo Takano, Koji Murakami,