Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10593195 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
A potent MCHR2 antagonist was discovered through SAR modification from a HTS lead. Compound 38 has good selectivity and good PK profile in multiple animal species.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Xiaoqi Chen, Jeff Mihalic, Pingchen Fan, Lingming Liang, Michelle Lindstrom, Sylvia Wong, Qiuping Ye, Ying Fu, Juan Jaen, Jin-Long Chen, Kang Dai, Leping Li,