Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10593243 | Bioorganic & Medicinal Chemistry Letters | 2012 | 4 Pages |
Abstract
Chitosan based microcapsule which encapsulated with phyllanthin was developed by simple coacervation. The composition and surface morphology of phyllanthin containing microcapsules were analyzed by Fourier Transform Infrared spectroscopy and Scanning Electron Microscopy, respectively. The release of phyllanthin from the microcapsules was found to be more than 60% after 120Â h. In vitro biological assays demonstrated that these phyllanthin containing microcapsules showed a stronger anti-oxidation potential on both human fibroblasts and keratinocytes as well as a better growth inhibitory activity towards Staphylococcus aureus.
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Authors
Pik-Ling Lam, Roberto Gambari, Joanne Yip, Marcus Chun-Wah Yuen, Kim-Hung Lam, Raymond Siu-Ming Wong, Xiao-Wen Wang, Johnny Cheuk-On Tang, Stanton Hon-Lung Kok, Chung-Hin Chui,