Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10593247 | Bioorganic & Medicinal Chemistry Letters | 2013 | 6 Pages |
Abstract
A series of methionine-proline anilides and their analogues were designed, synthesized and discovered as DENV 2 NS2B-NS3 inhibitors, and the most active NS2B-NS3 competitive inhibitors 1 and 2 with Ki values of 4.9 and 10.5 μM.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Guo-Chun Zhou, Zhibing Weng, Xiaoxia Shao, Fang Liu, Xin Nie, Jinsong Liu, Decai Wang, Chunguang Wang, Kai Guo,