| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10593269 | Bioorganic & Medicinal Chemistry Letters | 2013 | 5 Pages |
Abstract
Compound 10b3 (EC50 = 0.047 (wild-type) and 4.6 μM (mutant)) with dual structural conformations was designed via molecular hybridization, and could occupy the protein/solvent interface and the entrance channel of HIV-1 NNIBP simultaneously.
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Authors
Xuwang Chen, Xin Liu, Qing Meng, Ding Wang, Huiqing Liu, Erik De Clercq, Christophe Pannecouque, Jan Balzarini, Xinyong Liu,