| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10593445 | Bioorganic & Medicinal Chemistry Letters | 2012 | 5 Pages |
Abstract
The compound 5i found to be superior to diclofenac sodium and comparable with celecoxib for anti-inflammatory activity at a dose of 25Â mg/kg and showed quite less ulcerogenic potential among tested compound. The docking study revealed that compound 5i and celecoxib exhibited XP docking score â6.5485 and â5.9177, respectively.
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![Novel 3-substituted-1-aryl-5-phenyl-6-anilinopyrazolo[3,4-d]pyrimidin-4-ones: Docking, synthesis and pharmacological evaluation as a potential anti-inflammatory agents](/preview/png/10593445.png "First Page Preview: Novel 3-substituted-1-aryl-5-phenyl-6-anilinopyrazolo[3,4-d]pyrimidin-4-ones: Docking, synthesis and pharmacological evaluation as a potential anti-inflammatory agents")
Authors
Sandeep B. Yewale, Saurabh B. Ganorkar, Kamalkishor G. Baheti, Rupesh U. Shelke,