| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10593493 | Bioorganic & Medicinal Chemistry Letters | 2012 | 7 Pages |
Abstract
Six HEA core BACE-1 inhibitors with variations on the prime side alkyl substituted 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates were synthesized and evaluated for their BACE-1 in vitro and in vivo inhibitory activities.
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Authors
Christian Sund, Oscar Belda, Neera Borkakoti, Jimmy Lindberg, Dean Derbyshire, Lotta Vrang, Elizabeth Hamelink, Cathrine Ã
hgren, Esmeralda Woestenenk, Kristina Wikström, Anders Eneroth, Erik Lindström, Genadiy Kalayanov,